Osthole ameliorates wear particle-induced osteogenic impairment by mitigating endoplasmic reticulum stress via PERK signaling cascade

Abstract Background Periprosthetic osteolysis and subsequent aseptic loosening are the leading causes of failure following total joint arthroplasty. Osteogenic impairment induced by wear particles is regarded as a crucial contributing factor in the development of osteolysis, with endoplasmic reticul...

Descripció completa

Dades bibliogràfiques

Autors principals:	Xin Yu, Juan Jiang, Cheng Li, Yang Wang, Zhengrong Ren, Jianlun Hu, Tao Yuan, Yongjie Wu, Dongsheng Wang, Ziying Sun, Qi Wu, Bin Chen, Peng Fang, Hao Ding, Jia Meng, Hui Jiang, Jianning Zhao, Nirong Bao
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2024-12-01
Col·lecció:	Molecular Medicine
Matèries:	Osthole Aseptic loosening Osteolysis Osteoblast ER stress PERK signaling cascade
Accés en línia:	https://doi.org/10.1186/s10020-024-01034-z
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!