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Pyrosequencing dried blood spots reveals differences in HIV drug resistance between treatment naïve and experienced patients.

Dried blood spots (DBS) are an alternative specimen collection format for HIV-1 genotyping. DBS produce HIV genotyping results that are robust and equivalent to plasma when using conventional sequencing methods. However, using tagged, pooled pyrosequencing, we demonstrate that concordance between pl...

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主要な著者: Hezhao Ji, Yang Li, Binhua Liang, Richard Pilon, Paul MacPherson, Michèle Bergeron, John Kim, Morag Graham, Gary Van Domselaar, Paul Sandstrom, James Brooks
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2013-01-01
シリーズ:PLoS ONE
オンライン・アクセス:http://europepmc.org/articles/PMC3567018?pdf=render
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