Administration of L-Type Bovine Spongiform Encephalopathy to Macaques to Evaluate Zoonotic Potential

We administered L-type bovine spongiform encephalopathy prions to macaques to determine their potential for transmission to humans. After 75 months, no clinical symptoms appeared, and prions were undetectable in any tissue by Western blot or immunohistochemistry. Protein misfolding cyclic amplifica...

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Detalhes bibliográficos

Principais autores:	Morikazu Imamura, Ken’ichi Hagiwara, Minoru Tobiume, Minako Ohno, Hiromi Iguchi, Hanae Takatsuki, Tsuyoshi Mori, Ryuichiro Atarashi, Hiroaki Shibata, Fumiko Ono
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Centers for Disease Control and Prevention 2025-05-01
Colecção:	Emerging Infectious Diseases
Assuntos:	prions zoonoses oral transmission bovine spongiform encephalopathy cynomolgus macaques L-Type bovine spongiform encephalopathy
Acesso em linha:	https://wwwnc.cdc.gov/eid/article/31/5/24-1257_article
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