Pleomorphic and florid lobular carcinoma in situ of the Breast: A systematic review of current evidence and knowledge gaps

Introduction: Pleomorphic (PLCIS) and florid (FLCIS) lobular carcinoma in situ are uncommon entities, characterized by significant architectural distortion and cellular atypia. Their rarity poses three key clinical challenges: diagnostic variability, histologic upgrade and risk of local recurrence (...

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Principais autores:	Massimo Ferrucci, Daniele Passeri, Francesco Milardi, Giacomo Montagna, Anna C. Beck, Riccardo Audisio, Fredrick Wärnberg, Gianluca Franceschini, Lucio Fortunato, Matteo Ghilli, Valentina Guarneri, Alberto Marchet, Rocco Cappellesso, Angelo Paolo Dei Tos, Tari Ann King
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2026-04-01
Serija:	Breast
Teme:	Pleomorphic lobular carcinoma in situ Florid lobular carcinoma in situ Classic lobular carcinoma in situ Breast cancer Breast surgery Upgrade rate
Online dostop:	http://www.sciencedirect.com/science/article/pii/S0960977626000214
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