Structure-based virtual screening towards the discovery of novel thrombin inhibitors with Anti-HCC activities
IntroductionHepatic carcinoma (HCC) is one of the most lethal malignant tumors in the world, and new treatment regimens for this disease are urgently needed. Studies have shown that thrombin stimulates tumor progression by forming fibrin and activating platelets. Dabigatran etexilate, a thrombin inh...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2024-09-01
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| coleção: | Frontiers in Chemistry |
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| Acesso em linha: | https://www.frontiersin.org/articles/10.3389/fchem.2024.1451574/full |
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