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Prevalence of molecular markers of artemisinin and lumefantrine resistance among patients with uncomplicated Plasmodium falciparum malaria in three provinces in Angola, 2015

Abstract Background Artemisinin-based combination therapy is the first-line anti-malarial treatment for uncomplicated Plasmodium falciparum infection in Angola. To date, the prevalence of polymorphisms in the pfk13 gene, associated with artemisinin resistance, and pfmdr1, associated with lumefantrin...

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Principais autores: Dragan Ljolje, Pedro Rafael Dimbu, Julia Kelley, Ira Goldman, Douglas Nace, Aleixo Macaia, Eric S. Halsey, Pascal Ringwald, Filomeno Fortes, Venkatachalam Udhayakumar, Eldin Talundzic, Naomi W. Lucchi, Mateusz M. Plucinski
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2018-02-01
Series:Malaria Journal
Assuntos:
Malaria
Plasmodium falciparum
Angola
Haplotype
pfmdr1
pfk13
Acceso en liña:http://link.springer.com/article/10.1186/s12936-018-2233-5
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