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Refractory septic shock: our updated pragmatic approach

Abstract Despite the refinement in guidelines and improving outcomes, a subset of patients with septic shock fails to respond to treatment and progresses into refractory septic shock with an associated high morbidity and mortality. This population remains underrepresented in clinical trials due to t...

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Hoofdauteurs: Filippo Palmesino, Adam Woodman-Bailey, Fraser Hanks, Stephanie Khoo, Marlies Ostermann, Nicholas Ioannou, Christopher Meadows, Duncan Wyncoll
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2026-01-01
Reeks:Journal of Anesthesia, Analgesia and Critical Care
Onderwerpen:
Refractory septic shock
Multi-organ failure
Catecholamine toxicity
Toxic shock
Septic cardiomyopathy
Vasoplegic shock
Online toegang:https://doi.org/10.1186/s44158-025-00336-w
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