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Redesign of ultrasensitive and robust RecA gene circuit to sense DNA damage

Summary SOS box of the recA promoter, PVRecA from Vibrio natriegens was characterized, cloned and expressed in a probiotic strain E. coli Nissle 1917. This promoter was then rationally engineered according to predicted interactions between LexA repressor and PVRecA. The redesigned PVRecA‐AT promoter...

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Príomhchruthaitheoirí: Jack X. Chen, Boon Lim, Harrison Steel, Yizhi Song, Mengmeng Ji, Wei E. Huang
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Wiley 2021-11-01
Sraith:Microbial Biotechnology
Rochtain ar líne:https://doi.org/10.1111/1751-7915.13767
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