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A Novel Device-Integrated Drug Delivery System for Local Inhibition of Urinary Tract Infection

Background: Catheter-associated urinary tract infection (CAUTI) is a frequent community-acquired infection and the most common nosocomial infection. Here, we developed a novel antimicrobial catheter concept that utilizes a silicone-based interpenetrating polymer network (IPN) as balloon material to...

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Principais autores: Kristian Stærk, Rasmus Birkholm Grønnemose, Yaseelan Palarasah, Hans Jørn Kolmos, Lars Lund, Martin Alm, Peter Thomsen, Thomas Emil Andersen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-06-01
coleção:Frontiers in Microbiology
Assuntos:
uropathogenic Escherichia coli
CAUTI
large animal model
interpenetrating polymer network
urinary catheter
drug release
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fmicb.2021.685698/full
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