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Exon junction complex dependent mRNA localization is linked to centrosome organization during ciliogenesis

Exon junction complexes (EJCs) that mark untranslated mRNA are involved in transport, translation and nonsense-mediated mRNA decay. Here the authors show centrosomal localization of EJCs which appears to be required for both the localization of NIN mRNA around centrosomes and ciliogenesis.

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Autors principals: Oh Sung Kwon, Rahul Mishra, Adham Safieddine, Emeline Coleno, Quentin Alasseur, Marion Faucourt, Isabelle Barbosa, Edouard Bertrand, Nathalie Spassky, Hervé Le Hir
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2021-03-01
Col·lecció:Nature Communications
Accés en línia:https://doi.org/10.1038/s41467-021-21590-w
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