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Bax function in the absence of mitochondria in the primitive protozoan Giardia lamblia.

Bax-induced permeabilization of the mitochondrial outer membrane and release of cytochrome c are key events in apoptosis. Although Bax can compromise mitochondria in primitive unicellular organisms that lack a classical apoptotic machinery, it is still unclear if Bax alone is sufficient for this, or...

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Autors principals: Adrian B Hehl, Attila Regos, Elisabeth Schraner, André Schneider
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2007-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC1871612?pdf=render
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