Hexokinase regulates Mondo-mediated longevity via the PPP and organellar dynamics

The transcriptional complex Mondo/Max-like, MML-1/MXL-2, acts as a convergent transcriptional regulatory output of multiple longevity pathways in Caenorhabditis elegans. These transcription factors coordinate nutrient sensing with carbohydrate and lipid metabolism across the evolutionary spectrum. W...

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Autors principals:	Raymond Laboy, Marjana Ndoci, Shamsh Tabrez Syed, Maximilian Vonolfen, Eugen Ballhysa, Tim Droth, Klara Schilling, Anna Loehrke, Ilian Atanassov, Adam Antebi
Format:	Artigo
Idioma:	Inglês
Publicat:	eLife Sciences Publications Ltd 2025-08-01
Col·lecció:	eLife
Matèries:	MondoA MML-1 metabolism hexokinase longevity
Accés en línia:	https://elifesciences.org/articles/89225
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