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Epigenetic signatures of asthma: a comprehensive study of DNA methylation and clinical markers

Abstract Background Asthma, a complex respiratory disease, presents with inflammatory symptoms in the lungs, blood, and other tissues. We investigated the relationship between DNA methylation and 35 clinical markers of asthma. Methods The Illumina Infinium EPIC v1 methylation array was used to evalu...

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Principais autores: Austin J. Van Asselt, Jeffrey J. Beck, Casey T. Finnicum, Brandon N. Johnson, Noah Kallsen, Sarah Viet, Patricia Huizenga, Lannie Ligthart, Jouke-Jan Hottenga, René Pool, Anke H. Maitland-van der Zee, S. J. Vijverberg, Eco de Geus, Dorret I. Boomsma, Erik A. Ehli, Jenny van Dongen
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-11-01
coleção:Clinical Epigenetics
Assuntos:
Methylation
Asthma
Epigenetics
Epigenome-wide association
Microarrays
Acesso em linha:https://doi.org/10.1186/s13148-024-01765-0
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