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N-cadherin protects oral cancer cells from NK cell killing in the circulation by inducing NK cell functional exhaustion via the KLRG1 receptor

Background Circulating tumor cells (CTCs) can survive in the circulation and return to primary tumors through a self-seeding process. However, the mechanisms underlying CTCs escape from natural killer (NK) cell-mediated immune surveillance remain unclear.Method Self-seeded tumor cells were isolated...

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主要な著者: Qin Xu, Chao Lou, Kailiu Wu, Jianbo Shi, Zhenlin Dai
フォーマット: Artigo
言語:Inglês
出版事項: BMJ Publishing Group 2022-09-01
シリーズ:Journal for ImmunoTherapy of Cancer
オンライン・アクセス:https://jitc.bmj.com/content/10/9/e005061.full
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