FOXA1 mutations influence the therapeutic response of breast cancer by altering chromatin state
Forkhead box protein A1 (FOXA1) is a pioneer transcription factor that contributes to chromatin opening to allow binding of estrogen receptor (ER) in ER+ breast cancer. Mutations in FOXA1 are recurrent in breast cancer but the functional consequences of these mutations remain unknown. We identified...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis Group
2021-05-01
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| coleção: | Molecular & Cellular Oncology |
| Assuntos: | |
| Acesso em linha: | http://dx.doi.org/10.1080/23723556.2021.1891831 |
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