Tetrahydrobiopterin Slows the Progression of Atherosclerosis

We investigated whether oral tetrahydrobiopterin (BH4) treatment might slow the progression of atherosclerosis using hypercholesterolemic ApoE-knockout (KO) mice. We report that ingesting BH4 in drinking water is effective to inhibit atherogenesis in mice. Furthermore, we report that BH4 treatment i...

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主要な著者:	Kunihiro Suzuki, Hattori Yoshiyuki, Jojima Teruo, Tomizawa Atsuko, Okayasu Toshie, Kase Hiroyuki, Kawagoe Yoshiaki, Banba Nobuyuki, Monden Tsuyoshi, Nakanishi Nobuo, Kasai Kikuo
フォーマット:	Artigo
言語:	Inglês
出版事項:	De Gruyter 2007-02-01
シリーズ:	Pteridines
主題:	tetrahydrobiopterin apoe-ko mouse atherosclerosis endothelial function
オンライン･アクセス:	https://doi.org/10.1515/pteridines.2007.18.1.115
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