The incorporation of MALDI mass spectrometry imaging in studies to identify markers of toxicity following in utero opioid exposures in mouse fetuses

IntroductionIn 2015, the FDA released a Drug Safety Communication regarding a possible link between opioid exposure during early pregnancy and an increased risk of fetal neural tube defects (NTDs). At the time, the indications for opioid use during pregnancy were not changed due to incomplete matern...

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Principais autores:	Dustyn Barnette, Amy L. Inselman, Pravin Kaldhone, Grace S. Lee, Kelly Davis, Sumit Sarkar, Pritpal Malhi, J. Edward Fisher, Joseph P. Hanig, Richard D. Beger, E. Ellen Jones
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2024-12-01
Series:	Frontiers in Toxicology
Assuntos:	morphine exencephaly opioid MALDI MSI lipids hypoxia
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/ftox.2024.1452974/full
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