D-CAPS: an efficient CRISPR-Cas9-based phage defense system for E. coli

Escherichia coli is widely used in industrial chemical synthesis but faces significant challenges due to bacteriophage contamination, which reduces product quality and yield. Therefore, developing an efficient antiphage system is essential. In this study, we develop a CRISPR-Cas9-based antiphage sys...

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Detalhes bibliográficos

Principais autores:	Sun Mingjun, Gao Jie, Tang Hongjie, Wang Hengyi, Zhou Liyan, Song Chuan, Tian Yongqiang, Li Qi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	China Science Publishing & Media Ltd. 2025-04-01
coleção:	Acta Biochimica et Biophysica Sinica
Assuntos:	Keywords: bacteriophage contamination CRISPR-Cas9 <italic>E</italic>. <italic>coli</italic> T7 phage
Acesso em linha:	https://www.sciengine.com/doi/10.3724/abbs.2024208
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