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Establishment of an optimized orthotopic bladder cancer model in mice

Abstract Background Bladder cancer (BC) is one of the most common malignancies of the genitourinary system. Animal models offer an important tool to explore tumour initiation, progression, and therapeutic mechanisms. Our aim is to construct an optimized orthotopic BC model which is predictable, repr...

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Main Authors: Jinming Cai, Zhiwen Xie, Yilin Yan, Zhengnan Huang, Pengfei Tang, Xiangqian Cao, Zeyi Wang, Chenkai Yang, Mingyue Tan, Fang Zhang, Bing Shen
Format: Artigo
Language:Inglês
Published: BMC 2022-09-01
Series:BMC Urology
Subjects:
Bladder cancer
Orthotopic murine model
Microsyringes
MB49
Online Access:https://doi.org/10.1186/s12894-022-01093-6
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