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Synergistic Effect of a Pleuromutilin Derivative with Tetracycline against <i>Streptococcus suis</i> In Vitro and in the Neutropenic Thigh Infection Model

Tetracycline (TET) has been widely used in the treatment of <i>Streptococcus suis</i> (<i>S. suis</i>) infection. However, it was found that the efficacy of many antibiotics in <i>S. suis</i> decreased significantly, especially tetracycline. In this study, GML-12 (a novel pleuromutilin derivative) w...

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Principais autores: Fang Chen, Meng-Chao Wei, Yi-Dan Luo, Zhen Jin, You-Zhi Tang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-08-01
coleção:Molecules
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Acesso em linha:https://www.mdpi.com/1420-3049/25/15/3522
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