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The fate of pyruvate dictates cell growth by modulating cellular redox potential

Pyruvate occupies a central node in carbohydrate metabolism such that how it is produced and consumed can optimize a cell for energy production or biosynthetic capacity. This has been primarily studied in proliferating cells, but observations from the post-mitotic Drosophila fat body led us to hypot...

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Detalhes bibliográficos
Principais autores: Ashish G Toshniwal, Geanette Lam, Alex J Bott, Ahmad A Cluntun, Rachel Skabelund, Hyuck-Jin Nam, Dona R Wisidagama, Carl S Thummel, Jared Rutter
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications Ltd 2025-12-01
coleção:eLife
Assuntos:
Acesso em linha:https://elifesciences.org/articles/103705
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