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NAD-Linked Metabolism and Intervention in Short Telomere Syndromes and Murine Models of Telomere Dysfunction

Telomeres are specialized nucleoprotein structures that form protective caps at the ends of chromosomes. Short telomeres are a hallmark of aging and a principal defining feature of short telomere syndromes, including dyskeratosis congenita (DC). Emerging evidence suggests a crucial role for critical...

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Detalles Bibliográficos
Principais autores: Amanda J Stock, Yie Liu
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Aging
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fragi.2021.785171/full
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