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GLCCI1 alleviates airway remodeling in asthmatic mice by inhibiting ZEB1-mediated epithelial-mesenchymal transition

Abstract Background Asthma is a heterogeneous disease characterized by chronic airway inflammation and airway hyperresponsiveness. Our previous study found that glucocorticoid-induced transcript 1 (GLCCI1) is down-regulated in the lung tissues of asthmatic mice. This work attempted to determine the...

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Principais autores: Qing Yang, Wei Wang, Guofeng Zhu, Han Xun, Qiufen Xun
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2026-01-01
Colecção:Respiratory Research
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Acesso em linha:https://doi.org/10.1186/s12931-025-03476-3
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