Mapping of catecholaminergic denervation, neurodegeneration, and inflammation in 6-OHDA-treated Parkinson’s disease mice

Abstract Efforts to develop disease-modifying treatments for Parkinson’s disease (PD) have been hindered by the lack of animal models replicating all hallmarks of PD and the insufficient attention to extra-nigrostriatal regions pathologically critical for the prodromal appearance of non-motor sympto...

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Hlavní autoři:	Matteo Santoro, Rachel K. Lam, Sarah E. Blumenfeld, Weiqi Tan, Peter Ciari, Emily K. Chu, Nay L. Saw, Daniel Ryskamp Rijsketic, Jennifer S. Lin, Boris D. Heifets, Mehrdad Shamloo
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2025-02-01
Edice:	npj Parkinson's Disease
On-line přístup:	https://doi.org/10.1038/s41531-025-00872-w
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