All-in-one IQ toggle switches with high versatilities for fine-tuning of transgene expression in mammalian cells and tissues
The transgene toggling device is recognized as a powerful tool for gene- and cell-based biological research and precision medicine. However, many of these devices often operate in binary mode, exhibit unacceptable leakiness, suffer from transgene silencing, show cytotoxicity, and have low potency. H...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Elsevier
2024-03-01
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| Collection: | Molecular Therapy: Methods & Clinical Development |
| Sujets: | |
| Accès en ligne: | http://www.sciencedirect.com/science/article/pii/S2329050124000184 |
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