Synthesis of CF₃-Containing Spiro-[Indene-Proline] Derivatives via Rh(III)-Catalyzed C-H Activation/Annulation

An efficient method of accessing new CF₃-containing spiro-[indene-proline] derivatives has been developed based on a Cp*Rh(III)-catalyzed tandem C-H activation/[3+2]–annulation reaction of 5-aryl-2-(trifluoromethyl)-3,4-dihydro-2<i>H</i>-pyrrole-2-carboxylates with alkynes. An important f...

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Principais autores:	Alexandra S. Bubnova, Daria V. Vorobyeva, Ivan A. Godovikov, Alexander F. Smol’yakov, Sergey N. Osipov
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-11-01
coleção:	Molecules
Assuntos:	C-H activation spiro cyclization rhodium catalysis fluorinated proline derivatives
Acesso em linha:	https://www.mdpi.com/1420-3049/28/23/7809
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