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CD73 blockade alleviates collagen-induced arthritis by inhibiting synovial fibroblast activity

Objective(s): Rheumatoid arthritis (RA) is a chronic autoimmune disease with progressive cartilage erosion and joint destruction. CD73 plays a critical role in regulating inflammatory responses. This study aims to investigate the effects of CD73 blockade on RA progression and explore the potential m...

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Principais autores: Xia-nan Wu, Rui-cheng Li, Ruo-xuan Hei, Chong Liu, Zhao-wei Gao, Xi Wang, Ke Dong
Format: Artigo
Sprog:Inglês
Udgivet: Mashhad University of Medical Sciences 2026-05-01
Serier:Iranian Journal of Basic Medical Sciences
Fag:
bone destruction
cd73
rheumatoid arthritis
synovial fibroblasts
synovial inflammation
Online adgang:https://ijbms.mums.ac.ir/article_27573_3e68f0ed7eb3adafe2c2618d212b27db.pdf
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