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Suppression of ZBP1-mediated NLRP3 inflammasome by the tegument protein VP22 facilitates pseudorabies virus infection

ABSTRACT The interaction between Z-DNA binding protein 1 (ZBP1) and the NLR family pyrin domain-containing 3 (NLRP3) inflammasome has been uncovered in several viral infections. However, the role of this molecular pathway during infection with the alpha-herpesvirus pseudorabies virus (PRV) remains l...

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Huvudupphov: Zicheng Ma, Depeng Liu, Wandi Cao, Lei Guo, Kesen Liu, Juan Bai, Xingyi Li, Ping Jiang, Xing Liu
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Microbiology 2024-12-01
Serie:mBio
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Länkar:https://journals.asm.org/doi/10.1128/mbio.01945-24
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