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Molecular dissection of the replication system of plasmid pIGRK encoding two in-frame Rep proteins with antagonistic functions

Abstract Background Gene overlapping is a frequent phenomenon in microbial genomes. Excluding so-called “trivial overlapping”, there are significant implications of such genetic arrangements, including regulation of gene expression and modification of protein activity. It is also postulated that, be...

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Asıl Yazarlar: Paweł Wawrzyniak, Agnieszka Sobolewska-Ruta, Piotr Zaleski, Natalia Łukasiewicz, Paulina Kabaj, Piotr Kierył, Agata Gościk, Anna Bierczyńska-Krzysik, Piotr Baran, Anna Mazurkiewicz-Pisarek, Andrzej Płucienniczak, Dariusz Bartosik
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2019-11-01
Seri Bilgileri:BMC Microbiology
Konular:
Overlapping genes
Plasmid replication
Replication system
Rep protein
In-frame proteins
Transcription regulation
Online Erişim:http://link.springer.com/article/10.1186/s12866-019-1595-3
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