Prostatic fibroblast reprogramming by Interleukin-30 activates prostate cancer metastasis programs

Abstract Prostate cancer (PC) progression and mortality are largely driven by therapeutic resistance, increasingly linked to dynamic tumor–stroma interactions. However, the molecular basis of cancer–fibroblast crosstalk remains incompletely understood, particularly the contribution of Interleukin (I...

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Hlavní autoři:	Stefania Livia Ciummo, Carlo Sorrentino, Simona Marchetti, Cristiano Fieni, Paola Lanuti, Emma Di Carlo
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Springer 2026-06-01
Edice:	Molecular Biomedicine
Témata:	Cancer associated fibroblasts Prostate cancer Organ-on-chip Tumor microenvironment Metastasis Cytokines
On-line přístup:	https://doi.org/10.1186/s43556-026-00482-9
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