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Prognostic significance and response to immune checkpoint inhibitors of RIPK3, MLKL and necroptosis in non-small cell lung cancer

Abstract Lung cancer remains the leading cause of cancer death. Treatment with immune checkpoint inhibitor (ICI) alone or combination with chemotherapy served as first-line therapy in non-small cell lung cancer (NSCLC). However, only 20–50% of NSCLC patients respond to ICI. Necroptosis, an inflammat...

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Kaydedildi:
Asıl Yazarlar: Nattaya Duangthim, Thanpisit Lomphithak, Ryoko Saito-Koyama, Yasuhiro Miki, Chihiro Inoue, Ikuro Sato, Eisaku Miyauchi, Jiro Abe, Hironobu Sasano, Siriporn Jitkaew
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Portfolio 2024-09-01
Seri Bilgileri:Scientific Reports
Konular:
Immune checkpoint inhibitor
Immune microenvironment
Necroptosis
Non-small cell lung cancer
Receptor-interacting protein kinase 3
Online Erişim:https://doi.org/10.1038/s41598-024-72545-2
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