Molecular Profiling of Axial Spondyloarthritis Patients Reveals an Association between Innate and Adaptive Cell Populations and Therapeutic Response to Tumor Necrosis Factor Inhibitors

This study aims at identifying molecular biomarkers differentiating responders and non-responders to treatment with Tumor Necrosis Factor inhibitors (TNFi) among patients with axial spondyloarthritis (axSpA). Whole blood mRNA and plasma proteins were measured in a cohort of biologic-naïve axSpA pati...

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Principais autores:	Daniel Sobral, Ana Filipa Fernandes, Miguel Bernardes, Patrícia Pinto, Helena Santos, João Lagoas-Gomes, José Tavares-Costa, José A. P. Silva, João Madruga Dias, Alexandra Bernardo, Jean-Charles Gaillard, Jean Armengaud, Vladimir Benes, Lúcia Domingues, Sara Maia, Jaime C. Branco, Ana Varela Coelho, Fernando M. Pimentel-Santos
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2024-03-01
Series:	Biomolecules
Assuntos:	axial spondyloarthritis TNF inhibitor (adalimumab) treatment response disease activity innate immune system adaptive immune system
Acceso en liña:	https://www.mdpi.com/2218-273X/14/3/382
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