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DNA Double Strand Breaks and Chromosomal Translocations Induced by DNA Topoisomerase II

DNA double strand breaks (DSBs) are the most cytotoxic lesions of those occurring in the DNA and can lead to cell death or result in genome mutagenesis and chromosomal translocations. Although most of these rearrangements have detrimental effects for cellular survival, single events can provide clon...

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Détails bibliographiques
Auteur principal: Fernando Gómez-Herreros
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019-12-01
Collection:Frontiers in Molecular Biosciences
Sujets:
Accès en ligne:https://www.frontiersin.org/article/10.3389/fmolb.2019.00141/full
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