Receptor-mediated endocytosis by Megalin: Exploring its role in ligand interaction and disease mechanisms
This review comprehensively summarizes the interaction mechanisms between Megalin and several key ligands, including calcium ions, gentamicin, ApoE, ANKRA2, FVIII, TTR, STC1, RAP, and MMP-9, focusing on the specific amino acid binding sites involved. The analysis highlights the structural basis of t...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
KeAi Communications Co., Ltd.
2026-07-01
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| Collection: | Genes and Diseases |
| Sujets: | |
| Accès en ligne: | http://www.sciencedirect.com/science/article/pii/S2352304225003800 |
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