The Rieske iron-sulfur protein is a primary target of molecular hydrogen

The mechanisms underlying the biomedical effects of molecular hydrogen (H2) remain poorly understood and are often attributed to its selective reduction of hydroxyl radicals, based on the long-held notion that H2 is biologically inert. We demonstrate that H2 is biologically active, specifically targ...

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Główni autorzy:	Shuto Negishi, Mikako Ito, Tomoya Hasegawa, Hikaru Otake, Bisei Ohkawara, Akio Masuda, Hiroyuki Mino, Tyler W. LeBaron, Kinji Ohno
Format:	Artigo
Język:	Inglês
Wydane:	Elsevier 2025-12-01
Seria:	Redox Biology
Hasła przedmiotowe:	Molecular hydrogen Rieske iron-sulfur protein Mitochondrial unfolded protein response Hydrogenase
Dostęp online:	http://www.sciencedirect.com/science/article/pii/S2213231725004653
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