Lysosomal TFEB‐TRPML1 Axis in Astrocytes Modulates Depressive‐like Behaviors

Abstract Lysosomes are important cellular structures for human health as centers for recycling, signaling, metabolism and stress adaptation. However, the potential role of lysosomes in stress‐related emotions has long been overlooked. Here, it is found that lysosomal morphology in astrocytes is alte...

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Detalhes bibliográficos

Principais autores:	Jia‐Wen Mo, Peng‐Li Kong, Li Ding, Jun Fan, Jing Ren, Cheng‐Lin Lu, Fang Guo, Liang‐Yu Chen, Ran Mo, Qiu‐Ling Zhong, You‐Lu Wen, Ting‐Ting Gu, Qian‐Wen Wang, Shu‐Ji Li, Ting Guo, Tian‐Ming Gao, Xiong Cao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2024-11-01
Colecção:	Advanced Science
Assuntos:	astrocytes ATP depressive‐like behaviors lysosomes mucolipin TRP channel 1 transcription factor EB
Acesso em linha:	https://doi.org/10.1002/advs.202403389
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