miR-223 accelerates lipid droplets clearance in microglia following spinal cord injury by upregulating ABCA1

Abstract Background Spinal cord injury (SCI) is characterized by extensive demyelination and inflammatory responses. Facilitating the clearance of lipid droplets (LDs) within microglia contributes to creating a microenvironment that favors neural recovery and provides essential materials for subsequ...

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Principais autores:	Zhilin Ou, Yongquan Cheng, Hao Ma, Kai Chen, Qiong Lin, Jiayu Chen, Ruqin Guo, Zhiping Huang, Qixian Cheng, Nima Alaeiilkhchi, Qingan Zhu, Zucheng Huang, Hui Jiang
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2024-07-01
Series:	Journal of Translational Medicine
Assuntos:	Spinal cord injury (SCI) Microglia Lipid droplets miR-223 ATP-binding cassette transporter A1 (ABCA1)
Acceso en liña:	https://doi.org/10.1186/s12967-024-05480-5
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