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Agonist antagonist interactions at the rapidly desensitizing P2X3 receptor.

P2X3 receptors (P2XRs), as members of the purine receptor family, are deeply involved in chronic pain sensation and therefore, specific, competitive antagonists are of great interest for perspective pain management. Heretofore, Schild plot analysis has been commonly used for studying the interaction...

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Detalles Bibliográficos
Principais autores: Nick Helms, Maria Kowalski, Peter Illes, Thomas Riedel
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC3815160?pdf=render
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