Identification of a novel phage depolymerase against ST11 K64 carbapenem-resistant Klebsiella pneumoniae and its therapeutic potential

ABSTRACT Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a clinical pathogen with a high mortality rate, and its clinical management and infection control have become a serious challenge. Phage-encoded depolymerase cleaves the capsular polysaccharide, a major virulence factor of K. pneumoniae....

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Hlavní autoři:	Peini Yang, Bin Shan, Xing Hu, Li Xue, Guibo Song, Pingan He, Xu Yang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2025-04-01
Edice:	Journal of Bacteriology
Témata:	phage depolymerase CRKP capsular polysaccharide biofilm
On-line přístup:	https://journals.asm.org/doi/10.1128/jb.00387-24
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