Integrative transcriptomic profiling reveals molecular signatures of disease progression from gastroesophageal reflux disease to Barrett's esophagus: A foundation for single-cell resolution studies

Background: Barrett's esophagus (BE) represents a critical precancerous lesion arising from chronic gastroesophageal reflux disease (GERD), with significant risk of progression to esophageal adenocarcinoma. Despite advances in transcriptomic technologies, including single-cell RNA sequencing (scRNA-...

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Detalhes bibliográficos

Principais autores:	Shanshan Jiang, Xiumin Wang, Yujun Chen, Weihua Dong, Jing Xu, Chunlan Zhang, Chun Zhou, Chun Yu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2026-05-01
coleção:	SLAS Technology
Assuntos:	Gastroesophageal reflux disease (GERD) Barrett's esophagus Transcriptomics RNA sequencing
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2472630326000257
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