Increased acylcarnitines in infant heart failure indicate fatty acid oxidation inhibition: towards therapeutic options?

Abstract Aims Heart failure in adults is characterized by reduction of long‐chain fatty acid oxidation in favour of carbohydrate metabolism. This adaptive phenomenon becomes maladaptive because energy conversion decreases and lipid toxic derivatives known to impair cardiac function are accumulating....

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Autors principals:	Jean Issa, Pierre Lodewyckx, Hélène Blasco, Isabelle Benz‐de‐Bretagne, François Labarthe, Bruno Lefort
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 2023-10-01
Col·lecció:	ESC Heart Failure
Matèries:	Heart failure Children Dilated cardiomyopathy Acylcarnitines Fatty acid beta‐oxidation
Accés en línia:	https://doi.org/10.1002/ehf2.14449
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