Growth-promoting function of the cGAS-STING pathway in triple-negative breast cancer cells

The cGAS-STING axis is one of the key mechanisms guarding cells from pathogen invasion in the cytoplasmic compartment. Sensing of foreign DNA in the cytosol by the cGAS-STING axis triggers a stress cascade, culminating at stimulation of the protein kinase TBK1 and subsequently activation of inflamma...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Liang-Chih Liu, Yi-Chun Shen, Yuan-Liang Wang, Wan-Rong Wu, Ling-Chu Chang, Ya-Huey Chen, Chuan-Chun Lee, Shao-Chun Wang
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2022-08-01
Цуврал:	Frontiers in Oncology
Нөхцлүүд:	triple-negative breast cancer EGFR cGAS STING ssDNA cGAMP
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fonc.2022.851795/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!