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Reduced Lysosomal Acid Lipase Activity in Adult Patients With Non-alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease (NAFLD) is characterized by intra-hepatic fat accumulation and mechanisms involved in its pathogenesis are not fully explained. Lysosomal Acid Lipase (LAL) is a key enzyme in lipid metabolism. We investigated its activity in patients with fatty liver. LAL activity (...

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Autori principali: Francesco Baratta, Daniele Pastori, Maria Del Ben, Licia Polimeni, Giancarlo Labbadia, Serena Di Santo, Fiorella Piemonte, Giulia Tozzi, Francesco Violi, Francesco Angelico
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2015-07-01
Serie:EBioMedicine
Soggetti:
Lysosomal acid lipase
Non-alcoholic fatty liver disease
Non-alcoholic steatohepatitis
Metabolic syndrome
Statins
Accesso online:http://www.sciencedirect.com/science/article/pii/S2352396415300232
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