Dimensional memory in glioblastoma mechanics: Traction force analysis of cells cultured in 2D versus 3D collagen environments

Glioblastoma (GB) is one of the most aggressive and lethal brain tumors, characterized by rapid proliferation, diffuse infiltrative growth, therapeutic resistance, and molecular heterogeneity. A major challenge in studying GB is the lack of in vitro models that accurately replicate the tumor's cellu...

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Detalhes bibliográficos

Principais autores:	Mishal Khan, Philipp Kollenz, Maret Fritzenschaft, Fereydoon Taheri, Federico Colombo, Johannes W. Blumberg, Luise Schlotterose, Ulrich Sebastian Schwarz, Aldo Leal-Egaña, Christine Selhuber-Unkel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	KeAi Communications Co., Ltd. 2026-01-01
coleção:	Bioactive Materials
Assuntos:	Glioblastoma mechanics 2D v/s 3D culture 3D collagen substrate Dimensional memory Traction force microscopy
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2452199X25004323
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