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Implication of Opioid Receptors in the Antihypertensive Effect of a Novel Chicken Foot-Derived Peptide

The peptide AVFQHNCQE demonstrated to produce nitric oxide-mediated antihypertensive effect. This study investigates the bioavailability and the opioid-like activity of this peptide after its oral administration. For this purpose, in silico and in vitro approaches were used to study the peptide susc...

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Principais autores: Anna Mas-Capdevila, Lisard Iglesias-Carres, Anna Arola-Arnal, Gerard Aragonès, Begoña Muguerza, Francisca Isabel Bravo
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2020-07-01
Serier:Biomolecules
Fag:
bioactive peptides
blood pressure
Caco-2 cells
naloxone
nitric oxide
UHPLC-MS/MS
Online adgang:https://www.mdpi.com/2218-273X/10/7/992
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