Use of an antagonist of HMGB1 in mice affected by malignant mesothelioma: a preliminary ultrasound and optical imaging study

Abstract Background Malignant mesothelioma (MM) is an aggressive tumor, with a poor prognosis, usually unresectable due to late diagnosis, mainly treated with chemotherapy. BoxA, a truncated form of “high mobility group box 1” (HMGB1), acting as an HMGB1 antagonist, might exert a defensive action ag...

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Principais autores:	Massimo Venturini, Rosanna Mezzapelle, Salvatore La Marca, Laura Perani, Antonello Spinelli, Luca Crippa, Anna Colarieti, Anna Palmisano, Paolo Marra, Andrea Coppola, Federico Fontana, Giulio Carcano, Carlo Tacchetti, Marco Bianchi, Antonio Esposito, Massimo P. Crippa
Format:	Artigo
Jezik:	Inglês
Izdano:	SpringerOpen 2022-02-01
Serija:	European Radiology Experimental
Teme:	HMGB1 protein Mice (inbred BALB C) Mesothelioma (malignant) Optical imaging Ultrasonography
Online dostop:	https://doi.org/10.1186/s41747-021-00260-y
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