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Bipolar disorder integrative staging: incorporating biomarkers into progression across stages (BOARDING-PASS) – rationale and design

Bipolar disorder (BD) is a lifelong, recurrent condition with growing evidence supporting a neuroprogressive course, entailing the need to adopt staging models to guide stage-specific interventions. Although different approaches have been proposed, their application remains limited and largely based...

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Principais autores: Nicolaja Girone, Laura Cremaschi, Monica Macellaro, Camilla Gesi, Francesca Martella, Salvatore Saluzzi, Stefano Martinelli, Andrea Caporali, Ilenia Rosa, Clara Cavallotto, Annabella Di Giorgio, Claudio D’Addario, Giovanni Martinotti, Mauro Pettorruso, Mauro Gianni Perrucci, Francesco de Pasquale, Simonetta Gerevini, Emi Bondi, Bernardo Dell’Osso
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-10-01
Serier:Frontiers in Psychiatry
Fag:
bipolar disorder
neuroprogression
staging models
epigenetic
inflammation
machine learning
Online adgang:https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1646533/full
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