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Human neutrophils recognize group B streptococci via formylated peptide receptors and toll-like receptor 8

IntroductionNeutrophils, the most abundant leukocyte population, play a central role in host defense against group B Streptococcus (GBS), an encapsulated bacterium that frequently causes severe infections in humans, including sepsis and meningitis. However, the molecular pathways by which human neut...

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Principais autores: Luigi Fiore, Giuseppe Valerio De Gaetano, Federica Grasso, Francesco Coppolino, Agata Famà, Mariachiara Stifano, Annamaria Petrungaro, Federica Vita, Eugenia Quartarone, Chiara Cipollina, Germana Lentini, Concetta Beninati
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-05-01
coleção:Frontiers in Immunology
Assuntos:
bacterial RNA
formylated peptides
gram positive bacteria
IL-8
pattern recognition receptors
reactive oxygen species
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1828994/full
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