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Role of T Cell-To-Dendritic Cell Chemoattraction in T Cell Priming Initiation in the Lymph Node: An Agent-Based Modeling Study

The adaptive immune response is initiated in lymph nodes by contact between antigen-bearing dendritic cells (DCs) and antigen-specific T cells. A selected number of naïve T cells that recognize a specific antigen may proliferate into expanded clones, differentiate, and acquire an effector phenotype....

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Principais autores: Ivan Azarov, Kirill Peskov, Gabriel Helmlinger, Yuri Kosinsky
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-06-01
coleção:Frontiers in Immunology
Assuntos:
Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2019.01289/full
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