SENP3/FIS1-regulated PFC neural mitochondrial fragmentation underlies the mechanism of electroacupuncture attenuating depressive behavior in CUMS mice

ObjectiveElectroacupuncture (EA) is a common alternative treatment for depression, but its underlying mechanism remains unclear. Research suggests that its therapeutic effect may involve reducing SENP3/FIS1-regulated mitochondrial fragmentation, thereby mitigating neuronal damage in the prefrontal c...

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Hauptverfasser:	Shaoda Lai, Xiaoke Qiu, Peilin Lin, Jiayi Wu, Feifei Li, Ningjing Lai, Xin Li, Ting Tu, Jiping Zhang, Yong Huang, Zhinan Zhang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2026-01-01
Schriftenreihe:	Frontiers in Psychiatry
Schlagworte:	electroacupuncture depression prefrontal cortex mitochondrial fragmentation SENP3/FIS1
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1645757/full
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